Risk Factors Associated with the Occurrence of Preeclampsia in Women with Twin Pregnancies: Mini Review
نویسنده
چکیده
Aim: To summarize recent articles on the risk factors of preeclampsia in twin pregnancies from 2002 to 2014. Methods: Recent articles from 2002 to 2014 were searched using PubMed. Results: We found 8 articles analyzing the risk factors of preeclampsia in twin pregnancies and focused on the following three risk factors: i) egg (oocyte) donation, ii) chorionicity (dichorionic (DC) twins vs. monochorionic (MC) twins), iii) assisted reproductive technology (ART) (in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) vs. no-IVF/ICSI). Two articles evaluated the risk of egg (oocyte) donation for developing preeclampsia in twin pregnancies, and both reported that egg (oocyte) donation was a significant risk factor for the occurrence of PE in twin pregnancies. However, the effects of chorionicity and ART on the occurrence of PE in twins are still controversial. Conclusions: We attempted a mini-review on the risk factors of preeclampsia in women with twin pregnancies. Egg (oocyte) donation was a risk factor of preeclampsia in twin pregnancies. Since women with twin pregnancies have an almost three-fold increased risk of PE compared with those with singleton pregnancy, egg (oocyte) donor recipients with multiple pregnancies might face a very high risk of preeclampsia. Special Issue on Prediction of Preeclampsia
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